Read e-book online Atlas of Fundus Autofluorescence Imaging PDF
By Frank G. Holz, Steffen Schmitz-Valckenberg, Richard F. Spaide, Alan C. Bird
This lavishly illustrated specified atlas presents a finished and up to date evaluation of FAF imaging in retinal illnesses. It additionally compares FAF findings with different imaging options corresponding to fundus picture, fluorescein- and ICG angiography in addition to optical coherence tomography.
General ophthalmologists in addition to retina experts will locate this a really precious advisor which illustrates common FAF features of varied retinal illnesses.
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Extra info for Atlas of Fundus Autofluorescence Imaging
The laser is focused through a pinhole diaphragm to the focal plane (blue light). The reflected laser light is separated by a beam splitter from the incident laser beam path and is deflected through a second pinhole to reach a photosensitive detector (yellow light). Light originating outside the focal plane (red light) is effectively suppressed by the pinhole. Middle row left: Schematic illustration of the confocal optics. Light originating from the precise plane of focus (here, the retinal pigment epithelium) can pass through the pinhole and reach the detector.
Ophthalmologe 94:385–391 3. Bellmann, C, Rubin, GS, Kabanarou, SA, et al. (2003) Fundus autofluorescence imaging compared with different confocal scanning laser ophthalmoscopes. Br J Ophthalmol 87:1381–1386 4. Bindewald-Wittich, A, Han, M, Schmitz-Valckenberg, S, et al. (2006) Two-photon-excited fluorescence imaging of human RPE cells with a femtosecond Ti:sapphire laser. Invest Ophthalmol Vis Sci 47:4553–4557 5. Bindewald, A, Jorzik, JJ, Roth, F, Holz, FG (2005) [cSLO digital fundus autofluorescence imaging].
The decrease in FAF observed above age 70 has not been demonstrated in other studies although only a few showed significant increases at old age. The decrease in fluorescence at ages greater than 70 years could result, in part, from an undercorrection by our lens optical density estimates, from the presence of incipient atrophy, or from changes in fluorescence efficiency . Indeed, over 40% of the fluorescent granules in that age group are melanolipofuscin granules , and these have been shown to be less fluorescent than LF granules .
Atlas of Fundus Autofluorescence Imaging by Frank G. Holz, Steffen Schmitz-Valckenberg, Richard F. Spaide, Alan C. Bird