Kenneth R. Miller (Eds.)'s A Research Annual PDF


By Kenneth R. Miller (Eds.)

ISBN-10: 089232886X

ISBN-13: 9780892328864

As a self-discipline, phone biology has classically been outlined by means of the bounds which outline the bounds of its pursuits. those obstacles may possibly observe to situation -cell biologists learn fabric in the telephone - or they could observe to dimension - telephone biologists examine fabric above the extent of the macromolecule.
for a few years, the boundaries of procedure enforced those limitations as absolutely as any customized of the self-discipline. Our lack of ability to enquire constructions that could no longer be saw or molecules that may no longer be detected guaranteed that phone biology wouldn't go the bounds which associated the telephone to different degrees of association. because the 20th century nears its shut, even though, the improvement of a massive diversity of instruments and strategies, a few actual, a few chemical, a few organic, has replaced this example ceaselessly. telephone biology at the present time crosses the boundary, hyperlinks the molecule with the organelle, affiliates the mobile reaction with the

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It is of particular interest during embryogenesis when cell collectives are formed and induce specific differentiation events (Spemann, 1938). Early studies suggested that such cell-cell interactions were, in fact, specific recognition events and might be mediated by a large number of molecules that provided each cell with a unique address (Sperry, 1963); however, no molecules of such exquisite specificity have yet been identified. It has been proposed (Edelman, 1984) that such specificity at the molecular level is highly unlikely, but that the modulation of a small number of cell adhesion molecules (CAMs) is sufficient to account for a range of binding activities.

T. D. (1985) J. Biol. Chem. 260: 46-49. Woodget. J. R.. and Hunter, J. (1987) J. Biol. Chem. 262 4836-4843. THE STRUCTURE AND FUNCTION OF CELL ADHESION MOLECULES Bruce A. Cunningham OUTLINE I. 11. 111. IV. V. INTRODUCTION N-CAM A. Amino Acid Sequence B. mRNAs and the N-CAM Gene L-CAM AND RELATED MOLECULES Ng-CAM AND OTHER SECONDARY CAMS GENERAL CONSIDERATIONS REFERENCES Advances in Cell Biology, Volume 2, pages 25-54. Copyright 8 1988 by JAI Ress Inc. All rigbb of reproductioa in my fonn reserved.

128 383-388. Chuong. C. -M.. and Edelman. G.

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A Research Annual by Kenneth R. Miller (Eds.)

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